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AAT Bioquest

What are the functions of ferritin?

Posted August 22, 2024


Answer

Ferritin plays a key role in iron homeostasis, storing iron in the cells and releasing it in a controlled manner when needed for crucial cellular processes. It also serves a protective function, protecting DNA, proteins, and lipids from the potentially noxious effects of iron. 

Ferritin is also used as a serum marker of total iron stores in the body. Serum ferritin serves a vital role in diagnosing and managing iron deficiency as well as iron overload. 

Additional resources

A role for ferritin in hematopoiesis and the immune system

FerroBrite™ Green