What are the commonly used detection methods for ferroptosis?
Posted August 22, 2024
Answer
Ferroptosis is a type of regulatory cell death caused by an imbalance in the production and degradation of intracellular lipid and ROS (Reactive Oxygen Species). Studies suggest that ferroptosis plays a role in regulating various diseases including nervous system diseases and tumors, among others.
Currently, there are no specific techniques for detecting ferroptosis. However there are several types of detection technology being used for the purpose. These include:
- Microscopic imaging
- Flow cytometry
- Quantitative polymerase chain reaction (qPCR)
- Cell activity assay
- Western blotting
Lesser-used detection methods for ferroptosis include observing mitochondrial damage and quantifying oxygen-free radicals ROS (Reactive Oxygen Species).
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