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What proteins are involved in mitochondrial DNA replication?

Posted June 6, 2024


Cell Signaling
Cellular Processes
Cellular Structures and Organelles
Mitochondria
Physiological Probes
Answer

The proteins involved in mitochondrial DNA replication include: DNA polymerase γ, mitochondrial RNA polymerase (POLRMT/mtRNAP), Twinkle DNA helicase (c10orf2), and mitochondrial single-stranded DNA binding protein (mtSSB). 

Additional resources

The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis

Mitochondria

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