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AAT Bioquest

What do mitochondrial fission and fusion mean?

Posted June 6, 2024


Answer

Mitochondrial fusion refers to the merging of two mitochondria into a single organelle. The process is primarily regulated by mitofusins. In contrast, mitochondrial fission involves the division of a single mitochondrion into two separate organelles. The two proteins which facilitate this process are Fis1 and Drp1. 

Additional resources

Mitochondrial Fusion and Fission: The fine-tune balance for cellular homeostasis

Mitochondria

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