What are the differences between mRNA and tRNA?
Posted April 27, 2023
mRNA and tRNA are two different types of RNAs (ribonucleic acids). There are several differences between mRNA and tRNA, from their structure to the functions they perform.
Basis of differentiation |
mRNA |
tRNA |
Definition |
Is a type of RNA that acts as a messenger between genes and proteins |
Is a type of RNA that transfers specific amino acids into the ribosome for coding during protein synthesis |
Full name |
Messenger RNA |
Transfer RNA |
Structure |
Single-stranded, unfolded linear molecule |
3 dimensional complex structure composed of multiple hairpin loops , an acceptor arm, and a small variable loop |
Occurrence |
Synthesized in the nucleus and functions in the nucleus and cytoplasm |
Occurs and functions in the cytoplasm |
Size |
Varies depending on the coding sequence of the gene |
About 76 to 90 nucleotides in length |
Quantity in a cell |
A cell generally has a smaller amount of mRNA as compared to tRNA |
A cell has a larger amount of tRNA than mRNA |
Presence of codon/anticodon |
Carries a codon sequence that is complementary to the codon sequence of the gene – does not have an anticodon |
Carries an anticodon that is complementary to the codon on the mRNA |
Presence of sequence terminating nucleotides |
Absent |
Has CCA trinucleotides at one end of the molecule |
Function |
Serves as the messenger between genes and proteins, carrying genetic information contained in DNA to be used as a template for synthesizing protein |
Carries specific amino acid into the ribosome for protein synthesis |
Interaction with amino acids |
Does not attach to amino acids during protein synthesis |
Carries a specific amino acid by attaching to its acceptor arm |
Fate after completing its function |
Is destroyed after transcription |
Is reactivated by attaching to a second amino acid specific to it after releasing its first amino acid during translation |