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AAT Bioquest

What are the differences between cytoplasm and cytosol?

Posted June 17, 2024


Answer

Basis of differentiation

Cytosol

Cytoplasm

Definition

Is the fluid part of the cytoplasm

Is the gel-like substance filling the space between a cell's plasma membrane and its nucleus

Diversity

Relatively low

Relatively higher 

Functions

Transportation of molecules and signal transduction

Cytokinesis, signal transduction and nuclear division

Major reactions

All chemical reactions in prokaryotes take place in the cytosol

Large cellular activities like cell division and glycolysis take place in the cytoplasm

Composition

Soluble ions, water, water-soluble proteins 

Enzymes, carbohydrates, water, lipids, nucleic acids, inorganic ions, organelles, and cytosol

Size

It makes up 55% of the total cell volume

It makes up 45% of the total cell volume 

Additional resources

Difference Between Cytosol And Cytoplasm

Cell Structures and Organelles

ReadiPrep™ Nuclear/Cytoplasmic Fractionation Kit