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AAT Bioquest

How does protein electrophoresis differ from DNA electrophoresis?

Posted April 24, 2024


Answer

Protein and DNA electrophoresis are two types of gel electrophoresis methods with a few significant differences. 

Protein electrophoresis:

  • Is a technique used to separate proteins based on size and charge
  • The procedure uses a polyacrylamide gel, which has smaller pores
  • Is more time-intensive and requires specialized equipment and reagents

DNA electrophoresis:

  • Is a technique used to separate DNA based on size and charge
  • The procedure uses an agarose gel
  • Is less time-intensive and does not require specialized equipment or reagents
Additional resources

Electrophoresis of proteins and DNA on horizontal sodium dodecyl sulfate polyacrylamide gels

Gel Electrophoresis

Helixyte™ Green Nucleic Acid Gel Stain *10,000X DMSO Solution*