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Rhod-4™ amine
Rhod-4™ amine is an excellent building block that can be readily used to prepare a calcium-sensitive bioconjugate for monitoring calcium change spatially for a specific target. It can be conjugated to carboxy-containing biomolecules via activated esters or EDC chemistry. Rhod-4™ is a fluorescent calcium indicator dye commonly used in cell biology and neuroscience research. It belongs to the family of rhodol-based calcium. Rhod-4™ is a high-affinity calcium indicator dye that exhibits changes in fluorescence intensity upon binding to calcium ions. When Rhod-4™ binds to calcium, its fluorescence intensity increases dramatically, allowing researchers to measure and monitor changes in calcium levels. Compared to the traditional Rhod-2, Rhod-4™ is a superior replacement. It is a valuable tool in calcium imaging research, enabling the detection and quantification of intracellular calcium dynamics. It's fluorescence properties and calcium binding specificity make it suitable for studying calcium signaling in various cell types and biological systems.
Spectrum
Product family
| Name | Excitation (nm) | Emission (nm) | Quantum yield |
| Rhod-4™, AM | 523 | 551 | 0.11 |
References
View all 6 references: Citation Explorer
Dexamethasone Treatment Increases the Intracellular Calcium Level Through TRPV6 in A549 Cells.
Authors: Jeon, Bo-Hui and Yoo, Yeong-Min and Jung, Eui-Man and Jeung, Eui-Bae
Journal: International journal of molecular sciences (2020)
Authors: Jeon, Bo-Hui and Yoo, Yeong-Min and Jung, Eui-Man and Jeung, Eui-Bae
Journal: International journal of molecular sciences (2020)
Cigarette smoke extraxt influences intracellular calcium concentration in A549 cells.
Authors: Yoo, Y-M and Jung, E-M and Jeon, B-H and Tran, D N and Jeung, E-B
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (2020)
Authors: Yoo, Y-M and Jung, E-M and Jeon, B-H and Tran, D N and Jeung, E-B
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (2020)
A comparison of fluorescent Ca²⁺ indicators for imaging local Ca²⁺ signals in cultured cells.
Authors: Lock, Jeffrey T and Parker, Ian and Smith, Ian F
Journal: Cell calcium (2015): 638-48
Authors: Lock, Jeffrey T and Parker, Ian and Smith, Ian F
Journal: Cell calcium (2015): 638-48
Analysis of normal and rcdl Irish setter retinal proteins.
Authors: Cunnick, J and Takemoto, D
Journal: Progress in clinical and biological research (1989): 441-54
Authors: Cunnick, J and Takemoto, D
Journal: Progress in clinical and biological research (1989): 441-54
Rod/cone dysplasia in Irish setters. Presence of an altered rhodopsin.
Authors: Cunnick, J and Rider, M and Takemoto, L J and Takemoto, D J
Journal: The Biochemical journal (1988): 335-41
Authors: Cunnick, J and Rider, M and Takemoto, L J and Takemoto, D J
Journal: The Biochemical journal (1988): 335-41
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