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Psoralen TMP Succinimidyl Ester
Psoralens and their derivatives (such as 8-TMP and 4,5’,8-TMP) are well known to have unique crosslinking features to DNA. Psoralen TMP Succinimidyl Ester is an amino-reactive TMP derivative. It is an excellent building block for preparing TMP-labeled oligos from the readily available amino-modified oligos. The TMP-conjugated oligonucleotides can be used for sequence-specific crosslinking with a target DNA, thus enabling the application of psoralen-conjugated molecules in gene transcription inhibition, gene knockout, and other genomic applications. Psoralen TMP Succinimidyl Ester may also be used for preparing site-specific DNA/RNA probes via the conjugations with amino-containing biomolecules such as antibodies.
References
View all 50 references: Citation Explorer
Tracing the Photoaddition of Pharmaceutical Psoralens to DNA.
Authors: Diekmann, Janina and Theves, Isabell and Thom, Kristoffer A and Gilch, Peter
Journal: Molecules (Basel, Switzerland) (2020)
Authors: Diekmann, Janina and Theves, Isabell and Thom, Kristoffer A and Gilch, Peter
Journal: Molecules (Basel, Switzerland) (2020)
Nucleotide Excision Repair, XPA-1, and the Translesion Synthesis Complex, POLZ-1 and REV-1, Are Critical for Interstrand Cross-Link Repair in Caenorhabditis elegans Germ Cells.
Authors: Oh, Sinae and Bae, Woori and Alfhili, Mohammad A and Lee, Myon Hee
Journal: Biochemistry (2020): 3554-3561
Authors: Oh, Sinae and Bae, Woori and Alfhili, Mohammad A and Lee, Myon Hee
Journal: Biochemistry (2020): 3554-3561
Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.
Authors: Wilson, David M and Rieckher, Matthias and Williams, Ashley B and Schumacher, Björn
Journal: Nucleic acids research (2017): 9467-9480
Authors: Wilson, David M and Rieckher, Matthias and Williams, Ashley B and Schumacher, Björn
Journal: Nucleic acids research (2017): 9467-9480
Modulation of the UVB-induced lethality by furocoumarins in Staphylococcus aureus.
Authors: Silva, Emanuelle B F and Barbosa, Ideltônio J F and Barreto, Humberto M and Siqueira-Júnior, José P
Journal: Journal of photochemistry and photobiology. B, Biology (2014): 260-3
Authors: Silva, Emanuelle B F and Barbosa, Ideltônio J F and Barreto, Humberto M and Siqueira-Júnior, José P
Journal: Journal of photochemistry and photobiology. B, Biology (2014): 260-3
Methods for single/low-copy integration by ultraviolet and trimethylpsoralen treatment in Caenorhabditis elegans.
Authors: Kage-Nakadai, Eriko and Imae, Rieko and Yoshina, Sawako and Mitani, Shohei
Journal: Methods (San Diego, Calif.) (2014): 397-402
Authors: Kage-Nakadai, Eriko and Imae, Rieko and Yoshina, Sawako and Mitani, Shohei
Journal: Methods (San Diego, Calif.) (2014): 397-402
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