Concanavalin A, XFD488 Labeled *XFD488 Same Structure to Alexa Fluor™ 488*

XFD488 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 488 (Alexa Fluor® is the trademark of ThermoFisher). Concanavalin A (ConA) is a lectin that binds specifically to certain structures found in various sugars, glycoproteins and glycolipids. ConA is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. It is also used to purify glycosylated macromolecules in lectin affinity chromatography, as well as to study immune regulation by various immune cells. ConA binds specifically α-D-mannosyl and α-D-glucosyl residues (two hexoses differing only in the alcohol on carbon 2) in terminal position of ramified structures from B-Glycans. It has 4 binding sites, corresponding to the 4 subunits. Concanavalin A (Con A) is one of the most widely used lectins in cell biology. XFD488-labeled Concanavalin A (equivalent to Alexa Fluor® 488 conjugate of Con A, Alexa Fluor® is the trademark of ThermoFisher) exhibits the bright, green fluorescence (Ex/Em maxima ~495/519 nm). XFD488 labeled Con A selectively binds to a-mannopyranosyl and a-glucopyranosyl residues.