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Acridinium Biotin Conjugate

Acridinium biotin is a conjugate of acridinium ester and biotin. It is a chemiluminescent label that can be used to detect antibodies or antigens in a wide range of immunoassays. For example, it may be used to label antibodies or antigens that can be detected by streptavidin-coated magnetic beads in a chemiluminescent immunoassay system. Since biotin is a small molecule that can bind to streptavidin with high affinity and specificity, the acridinium biotin reagent can be used in a variety of immunological applications in combination of numerous commercially available streptavidin conjugates.

References

View all 13 references: Citation Explorer
Magnetic Nanoparticle-Based Automatic Chemiluminescent Enzyme Immunoassay for Golgi Protein 73 and the Clinical Assessment.
Authors: Wei, Xuefei and Xia, Yanyan and Shen, Mengjiao and Yang, Yue and Jin, Jing and Xu, Hongpan and Li, Zhiyang
Journal: Journal of nanoscience and nanotechnology (2019): 1971-1977
Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients.
Authors: Reily, Colin and Rizk, Dana V and Julian, Bruce A and Novak, Jan
Journal: BioTechniques (2018): 71-77
A rapid and sensitive chemiluminescent immunoassay of total thyroxin with DMAE x NHS-Labeled.
Authors: Yin, Dongguang and Cui, Daxiang and Gao, Feng and He, Rong and He, Youfeng and Liu, Yibing and Shen, Decun and Wu, Minghong
Journal: Journal of immunoassay & immunochemistry (2008): 257-65
Regiodependent luminescence quenching of biotinylated N-sulfonyl-acridinium-9-carboxamides by avidin.
Authors: Adamczyk, Maciej and Mattingly, Phillip G and Moore, Jeffrey A and Pan, You
Journal: Organic letters (2003): 3779-82
Single-nucleotide polymorphism analysis by hybridization protection assay on solid support.
Authors: Goto, Susumu and Takahashi, Aki and Kamisango, Keiichi and Matsubara, Koichi
Journal: Analytical biochemistry (2002): 25-32
Page updated on November 23, 2024

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Catalog Number26050
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Physical properties

Molecular weight

928.03

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
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