Which cytokines are involved in inflammation?

Pro-inflammatory cytokines are involved in inflammation. They include interleukin-1 (IL-1), IL-12, and IL-18, interferon gamma (IFNγ), tumor necrosis factor alpha (TNF-α), and granulocyte-macrophage colony stimulating factor (GM-CSF). These cytokines play a key role in mediating the innate immune response.

Pro-inflammatory cytokines are released by immune cells that promote inflammation such as macrophages and helper T cells (Th). Excessive chronic production of these cytokines contribute to inflammatory diseases such as cancer and atherosclerosis.