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AAT Bioquest

What is the significance of bone remodeling?

Posted June 17, 2024


Answer

Bone remodeling entails the resorption or removal of damaged or old bone which is replaced by newer, healthier bone tissue. It is significant because it serves to adjust bone architecture and shape the skeleton to adapt to the body’s changing mechanical needs. It also plays crucial roles in regulating plasma calcium homeostasis, repairing micro-damages in bone matrix from everyday stress, and preventing accumulation of old bone.

Additional resources

Bone modeling and remodeling: potential as therapeutic targets for the treatment of osteoporosis

Immunohistochemistry (IHC)

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