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AAT Bioquest

What does a CD45 marker stain?

Posted August 11, 2022


Answer

CD45 is a marker of all hematopoietic cells except platelets and red blood cells (mature erythrocytes). CD45, a receptor-type protein tyrosine phosphatase, is a signaling molecule that regulates many cellular processes such as cell growth, differentiation, and more. It is an essential regulator of B and T cell antigen receptor signaling. 

Additional resources

APC/Cy7 Anti-human CD45 Antibody *2D1*

Cluster of Differentiation (CD Antibodies)

Cell Cytotoxicity

Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines