What are the types of combinatorial antibody libraries?

There are four types of combinatorial antibody libraries: immune, naive, semi-synthetic, and synthetic libraries.

• Immune libraries use antibodies from immunized humans or animals.
• Naïve libraries use antibodies from unimmunized subjects or synthetic human genes.
• Semi-synthetic libraries are controlled by oligonucleotides synthesis.
• Synthetic libraries are composed of fully artificial, random codons assimilated into CDRs.