What are the pros of membrane asymmetry cell viability assays?

Pros of membrane asymmetry cell viability assays: 

• F2N12S (4′-N,N-diethylamino-6-(N-dodecyl-N-methyl-N-(3-sulfopropyl))ammoniomethyl-3-hydroxyflavone) staining is very quick (5 minutes).
• F2N12S probe is a tiny molecule and is not sensitive to proteases.
• Fixation is possible with annexin V staining.
• Both dyes – F2N12S and annexin V – can be combined with other markers for intracellular functional analysis or for cell surface phenotyping.
• Membrane permeabilization is not needed for either of the dyes.