What are the limitations of RNA interference (RNAi)?
Posted August 15, 2024
Answer
One limitation is the off-target effects. RNAi can sometimes affect unintended genes, leading to potential side effects. Another limitation is possible delivery issues. Introducing siRNA into cells effectively remains a challenge, although advancements in delivery reagents are improving this process.
Additional resources
RNA Interference–Based Therapy and Its Delivery Systems
Gene Expression Analysis & Genotyping
Portelite™ Fluorimetric RNA Quantitation Kit*Optimized for Cytocite™ and Qubit™ Fluorometers*