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AAT Bioquest

What are the functions of bone lining cells?

Posted June 17, 2024


Answer

Bone lining cells serve several functions:

  • Maintain mineral homeostasis by regulating bone fluids and the fluxes of ions between bone fluid and interstitial fluid compartments
  • Play a complementary role in maintaining bone matrix
  • Are an integral component of the marrow stromal system and play a vital role in hematopoiesis by regulating the inductive microenvironment
  • May play a role in propagating the activation signal that stimulates bone remodeling and bone resorption
Additional resources

Bone lining cells: structure and function

Immunohistochemistry (IHC)

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