What are the differences between open and closed mitosis?
Posted November 30, 2023
Basis of differentiation |
Open mitosis |
Closed mitosis |
Definition |
Open mitosis is the separation of chromosomes subsequent to nuclear envelope breakdown (NEBD) |
Closed mitosis is the separation of chromosomes and spindle formation without NEBD |
Occurrence |
In multicellular organisms |
Occurs in lower eukaryotes (typically in fungi) |
Mechanism |
The nuclear envelope disintegrates prior to the chromosomes segregating |
Chromosome division occurs within the cell nucleus |
Significance of evolution |
Open mitosis has been altered several times during evolution |
Is the oldest mechanism of eukaryotic cell division |
Spindle formation |
Spindle fibers form within the nucleus |
Spindle fibers form outside of the nucleus |
Nuclear membrane |
The nuclear membrane disintegrates and then re-forms around 2 sets of segregated chromosomes |
The nuclear membrane remains intact |
The cell biology of open and closed mitosis
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