What are the differences between eukaryotic transcription and prokaryotic transcription?
Posted January 6, 2023
Basis of differentiation |
Eukaryotic transcription |
Prokaryotic transcription |
Location |
Eukaryotic transcription occurs in the cell nucleus |
Prokaryotic transcription occurs in the cell cytoplasm |
Mechanism of transcription |
A pre-mRNA molecule is formed and processed to yield a mature mRNA |
mRNA is transcribed directly from the template DNA molecule |
Number of RNA polymerase subunits |
RNA polymerase has 10-17 subunits |
RNA polymerase has 5 subunits |
Occurance of transcription and translation |
Transcription occurs in nucleus, and translation occurs outside the nucleus at different times |
Prokaryotic transcription and translation occur simultaneously in cytoplasm |
Produced mRNA |
Are monocistronic |
Are polycistronic |
Post transcriptional modifications |
Occurs during eukaryotic transcription |
Do not occur |
Transcriptional factors |
Requires transcriptional factors to bind RNA polymerase to promoter |
Requires a sigma factor to bind to promoter |
RHO factor |
Eukaryotes do not need RHO factors |
Termination of transcription requires a RHO factor |
Prokaryotic Transcription and Translation Are Coupled