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AAT Bioquest

What are the benefits of capillary zone electrophoresis (CZE)?

Posted May 29, 2024


Answer

One advantage is that CZE requires minimal sample preparation compared to other analytical techniques since it uses an electric field. CZE also offers excellent resolution for separating analytes. Another pro is that in CZE the flow profile is flat, meaning that the analytes migrate through the capillary at nearly constant velocities. Additionally, CZE offers a greater peak capacity compared to some other separation methods, allowing for the simultaneous analysis of a larger number of analytes within a single run. CZE is also known for its rapid separation capabilities. It can achieve high separation efficiency in short time periods, often completing analyses within minutes to an hour. 

Additional resources

Improvement of Capillary Electrophoretic Enantioseparation of Fluoxetine by a Cationic Additive

Gel Electrophoresis

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