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AAT Bioquest

What are the advantages of traditional gel electrophoresis over capillary electrophoresis?

Posted May 29, 2024


Answer

One advantage is that traditional gel electrophoresis is known for being cost-effective compared to capillary electrophoresis, which often involves more automation and higher upfront costs. Another advantage of traditional gel electrophoresis is its ability to simultaneously visualize results from multiple samples in a parallel format. With a single slab gel, numerous samples can be run concurrently, whereas capillary electrophoresis typically allows only one sample to run per capillary, requiring multichannel setups for parallel runs. Traditional gel electrophoresis using agarose gels is also the most straightforward technique for visualizing and analyzing PCR products, enabling researchers to confirm the presence and size of the amplified DNA fragments.

Additional resources

Capillary Electrophoresis

Gel Electrophoresis

Gelite™ Green Nucleic Acid Gel Staining Kit