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AAT Bioquest

What are osteocytes in biology?

Posted June 17, 2024


Answer

Osteocytes are the most abundant type of bone cells. They lie within the substance of fully formed bone, occupying a small chamber known as a lacuna, which is contained in the calcified matrix of bone. Each lacuna houses one osteocyte. 

The cells are flat and almond shaped with a length of about15 micrometers and a depth of about 7 micrometers. A mature osteocyte has a single membraned-nucleus with one or two nuclei, rough endoplasmic reticulum, and reduced Golgi complex. 

Osteocytes are derived from osteoblasts, which are bone-forming cells. They are long lived bone cells. Their viability is maintained by means of small channels known as canaliculi, which facilitate the exchange of nutrients and waste products. 

Additional resources

Functions of the osteocyte network in the regulation of bone mass

Immunohistochemistry (IHC)

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