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AAT Bioquest

How is pKa different from pH?

Posted May 24, 2024


Answer

pKa

  • Is defined as the negative value of the logarithm of Ka
  • Indicates whether an acid is a weak or strong acid
  • High pKa of an acid indicates that it is a weak acid, while low pKa indicates that it is a strong acid
  • Is dependent on the concentration of H+ ions, acid concentration, and conjugate base

pH

  • Is defined as the logarithmic value of the inverse of H+ concentration
  • Indicates whether a system is acidic or basic
  • High pH value above 7 indicates a basic solution, while low pH value below 7 indicates an acidic solution
  • Is dependent on concentration of H+ ions
Additional resources

Arginine: Its pKa value revisited

pKa to pKb Conversion Table

pKa and pKb Reference Table