logo
AAT Bioquest

How does bone remodeling work?

Posted June 17, 2024


Answer

Bone remodeling occurs throughout a person’s lifetime and involves resorption by osteoclasts and replacement by osteoblasts. The process takes place over three phases: 

  • Activation of osteoblasts, a type of bone cell
  • Resorption, in which osteoclasts digest old and damaged bone
  • Bone formation, in which osteoblasts lay down new bone until the resorbed bone is completely replaced

An individual’s entire skeleton is replaced every 10 years. 

Additional resources

Physiology, Bone Remodeling

Immunohistochemistry (IHC)

ReadiUse™ Stayright™ Purple *HRP Chromogen Premixed with Hydrogen Peroxide*