What are the types of introns?
Posted June 22, 2020
Answer
There are at least four distinct types of introns:
- Group I introns: They are large self-splicing ribozymes that can catalyze their own excision from mRNA, tRNA and rRNA precursors. The secondary structure of group I introns has a nine-looped stem, which is required for splicing.
- Group II Introns: They are also self-splicing ribozymes that are found in rRNA, tRNA and mRNA, but they cut themselves differently than group I introns. Besides, the splicing of group II Introns involves the formation of a lariat structure.
- Nuclear pre-mRNA Introns: They are found in the nucleus in protein-coding genes that are removed by spliceosomes.
- Transfer RNA introns: They are found in tRNA genes and need proteins (enzymes) to be removed.
Additional resources
6-ROX glycine *25 uM fluorescence reference solution for PCR reactions*