What are the 3 binding sites for tRNA in the ribosome?

The 3 binding sites for tRNA are called aminoacyl site (abbreviated A), the peptidyl site (abbreviated P) and the exit site (abbreviated E), which are oriented 5’ to 3’ E-P-A with respect to the mRNA.

• The A site binds to the incoming aminoacyl tRNA, which carries the new amino acid to be added to the polypeptide chain.
• The P site holds the tRNA with the growing polypeptide chain.
• The E site serves as a threshold. It holds the tRNA without its amino acid, which is then released by ribosome.