What are the differences between prokaryotes and eukaryotes?
Posted February 3, 2021
Answer
Based on the structure and functions, cells are broadly classified as prokaryotic cell and eukaryotic cell Prokaryotes are small, single-cellular organisms while eukaryotes are large, complex organisms. There are several differences between these two types of cells.
Basic for comparison | Prokaryotes | Eukaryotes |
Cell type & complexity | Unicellular, simple | Multicellular, complex |
Size & Structure | 0.5-3um, cell wall present | 2-100um, cell wall absent except in few plant cells and fungus |
Presence & Structure of Nucleus | Does not have a well-defined nucleus. DNA is contained in an open region called a nucleoid | Has a well-defined nucleus enclosed in a nuclear membrane |
Shape & Structure of DNA | Circular, double-stranded DNA | Linear, double-stranded DNA |
Presence of organelles | Mitochondria, Golgi Apparatus, and Endoplasmic Reticulum are absent | Mitochondria, Golgi Apparatus, and Endoplasmic Reticulum are present |
Lysosomes & peroxisomes | Absent | Present |
Mesosomes | Present | Absent |
Chloroplasts | Absent – chlorophyll is dispersed in cytoplasm | Present in plants |
Number of chromosomes | One, not true chromosome called plasmid | More than one |
Origin of replication | Single origin | Multiple origins |
Ribosomes | May be free in cytoplasm or bound to cell membrane | Attached to rough endoplasmic reticulum |
Cell Division | Binary fission | Mitosis |
Transcription & translation | Both occur simultaneously | Transcription occurs in nucleus followed by translation in cytoplasm |
Site of DNA replication | Cytoplasm | Nucleus |
Genetic recombination | Partial, unidirectional transfer | Meiosis and fusion of gametes |
DNA wrapping on proteins | Multiple proteins simultaneously fold and condense DNA, which is then organized in various conformations | DNA is wrapped around proteins known as histones |
Mode of reproduction | Asexual (binary fission) | Mostly sexual |
Mode of respiration | Via cytoplasmic membrane | Via mitochondria |
Major groups | Archaea, Bacteria, Bluegreen Algae | Algae, Plants, Animals, Fungi |
Additional resources
Prokaryotic and eukaryotic chromosomes: what's the difference?