XFD647 Anti-human CD107 Antibody *H4B4, XFD647 Same Structure to Alexa Fluor™ 647*

H4B4 is an anti-human monoclonal antibody that targets the CD107b antigen. CD107b (sometimes called LAMP2 or LAMPb) is a 45 kD transmembrane protein that is found on the surface of cells like granulocytes and endothelial cells. In many organisms, CD107 is a suppressor of protein-containing complex assembly. Additionally, it has been associated with essential biological processes like chaperone-mediated autophagy, particularly protein targeting to lysosome involved in chaperone-mediated autophagy. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands. CD107 is a relatively rare antibody target, with fewer than 800 publications in the last decade. Even still, CD107b is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of protein trafficking and clearance and neuroscience. This antibody was purified through affinity chromatography and conjugated to XFD647 (ex/em = 650/671 nm). XFD647 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 647 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 642 nm laser and 702/87 nm bandpass filter (for example, as in the Luminex Amnis CellStream).

Page updated on December 17, 2024