Tide Quencher™ 2 azide [TQ2 azide]

Name: Tide Quencher™ 2 azide [TQ2 azide]
Brand: AAT Bioquest
SKU: 2211
Price: 227 USD
Availability: InStock

TQ2 is designed to be a superior quencher to FAM, HEX, TET, JOE, TF2 and rhodamine 6G. TQ2 has (a). much stronger absorption; (b). much higher quenching efficiency; and (c). versatile reactive forms for labeling oligonucleotides and peptides. This TQ2 product is reactive to alkynes, and useful for click chemistry.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Tide Quencher™ 2 azide [TQ2 azide] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	221.946 µL	1.11 mL	2.219 mL	11.097 mL	22.195 mL
5 mM	44.389 µL	221.946 µL	443.892 µL	2.219 mL	4.439 mL
10 mM	22.195 µL	110.973 µL	221.946 µL	1.11 mL	2.219 mL

Molarity calculator

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Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
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Spectrum

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Product family

Name	Extinction coefficient (cm ^-1 M ^-1)	Correction Factor (260 nm)	Correction Factor (280 nm)
Tide Quencher™ 4WS azide [TQ4WS azide]	90000¹	0.149	0.136
Tide Quencher™ 6WS azide [TQ6WS azide]	130000	0.120	0.102
Tide Quencher™ 1 azide [TQ1 azide]	20000	0.147	0.194
Tide Quencher™ 2 CPG [TQ2 CPG] 500 Å	21000	0.100	0.12
Tide Quencher™ 2 CPG [TQ2 CPG] 1000 Å	21000	0.100	0.12
Tide Quencher™ 2 phosphoramidite [TQ2 phosphoramidite]	21000	0.100	0.12
Tide Quencher™ 3 azide [TQ3 azide]	22000	0.085	0.091
Tide Quencher™ 5WS azide [TQ5WS azide]	130000	0.072	0.082
Tide Quencher™ 7WS azide [TQ7WS azide]	140000	0.072	0.091
Tide Fluor™ 2 azide [TF2 azide]	75000	-	0.09
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Citations

View all 8 citations: Citation Explorer

A Modular Customizable Ligand-Conjugate (LC) System Targeting Ghrelin O-Acyltransferase
Authors: Ford, Amber L and Taft, Caine W and Sprague-Getsy, Andrea M and Carlson, Gracie C and Mate, Nilamber A and Sieburg, Michelle A and Chisholm, John D and Hougland, James L
Journal: (2024)

A mechanistic model to predict effects of cathepsin B and cystatin C on β-amyloid aggregation and degradation
Authors: Perlenfein, Tyler J and Murphy, Regina M
Journal: Journal of Biological Chemistry (2017): jbc--M117

Real-Time Detection of a Self-Replicating RNA Enzyme
Authors: Olea, Charles and Joyce, Gerald F
Journal: Molecules (2016): 1310

Maternal serum glycosylated fibronectin as a point-of-care biomarker for assessment of preeclampsia
Authors: Rasanen, Juha and Quinn, Matthew J and Laurie, Amber and Bean, Eric and Roberts, Charles T and Nagalla, Srinivasa R and Gravett, Michael G
Journal: American journal of obstetrics and gynecology (2015): 82--e1

Development of Multi-Parametric/Multimodal Spectroscopy Apparatus for Characterization of Functional Interfaces
Authors: Zhou, Lang and Arugula, Mary and Easley, Christopher J and Shannon, Curtis and Simonian, Aleks and r, undefined
Journal: ECS Transactions (2015): 9--16

References

View all 25 references: Citation Explorer

Evaluation of tetramethylrhodamine and black hole quencher 1 labeled probes and five commercial amplification mixes in TaqMan real-time RT-PCR assays for respiratory pathogens
Authors: Yang GP, Erdman DD, Tondella ML, Fields BS.
Journal: J Virol Methods (2009): 288

Time-resolved FRET method for typing polymorphic alleles of the human leukocyte antigen system by using a single DNA probe
Authors: Andreoni A, Bondani M, Nardo L.
Journal: Photochem Photobiol Sci (2009): 1202

Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin "quencher-chaser": a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer
Authors: Ogawa M, Kosaka N, Choyke PL, Kobayashi H.
Journal: Bioconjug Chem (2009): 147

The detection of platelet derived growth factor using decoupling of quencher-oligonucleotide from aptamer/quantum dot bioconjugates
Authors: Kim GI, Kim KW, Oh MK, Sung YM.
Journal: Nanotechnology (2009): 175503

Development of a cell-based hepatitis C virus infection fluorescent resonance energy transfer assay for high-throughput antiviral compound screening
Authors: Yu X, Sainz B, Jr., Uprichard SL.
Journal: Antimicrob Agents Chemother (2009): 4311

Page updated on December 17, 2024

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Physical properties

Molecular weight	450.56
Solvent	DMSO

Spectral properties

Absorbance (nm)	516
Correction Factor (260 nm)	0.100
Correction Factor (280 nm)	0.12
Extinction coefficient (cm ^-1 M ^-1)	21000

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200