Purified Mouse Anti-non-human primates/rat TCR α/β Antibody *R73, monoclonal*

T cell receptor α chain constant is a 18 kDa transmembrane protein that can be expressed in the integral component of membrane, plasma membrane and T cell receptor complex of cells. In Homo sapiens, T cell receptor α chain constant is the subject of intensive study due to the fact that it is a component of the T cell receptor signaling pathway. Sequencing of T cell receptor α chain constant has shown it contains 2 conserved structural units: Ig-like C1-type and cytoplasmic domain, and furthermore, aids in organismal processes, in particular, adaptive immune response. T cell receptor α chain constant is thought to be essential to immune response. Mutations and abnormalities in T cell receptor α chain constant have been thought to be involved with a number of diseases, for instance, immunodeficiency 7 (IMD7). Immunodeficiency 7, an autosomal recessive inheritancedisorder characterized by recurrent infections, lymphadenopathy and autoimmunity, has especially been of interest to scientists.

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