Purified Mouse Anti-human/pig HLA-DQ1/DQ3 Antibody *HL-37, monoclonal*

HLA class II histocompatibility antigen, DQ α 1 chain (also known as DC-1 α chain, HLA-DCA, DC-α or MHC class II DQA1) is a transmembrane protein with a molecular weight of 32 kDa, located in the transport vesicle membrane, endosome membrane and membrane of cells. In humans, DC-1 α chain reacts with peptide antigen. DC-1 α chain has been closely linked to important functions like MHC class II receptor activity. It is the subject of intensive examination stemming from the fact that it is a component of the T cell receptor signaling pathway and interferon-γ-mediated signaling pathway. Sequencing of DC-1 α chain has supported it contains 3 conserved structural units: Ig-like C1-type, cytoplasmic and extracellular domaind. HLA class II histocompatibility antigen, DQ α 1 chain has been found to be involved in organismal processes, for example, immune response, adaptive immune response and antigen processing and presentation of exogenous peptide antigen via MHC class II.

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