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Purified Mouse Anti-human PD-1 Antibody *AHC0211, Monoclonal, IgG2b*
Programmed cell death protein 1 (Protein PD-1) is a 32 kDa transmembrane protein that can be expressed in the plasma membrane of cells. In humans, protein PD-1 is a negative regulator of apoptotic process, tolerance induction and immune response. But it also acts to positively regulate T cell apoptotic process. Protein PD-1 is thought to be essential to immune response. Sequencing of protein PD-1 has shown it contains 3 types of conserved structural units: extracellular, cytoplasmic and Ig-like V-type domain. Protein PD-1 is thought to be essential to organismal processes, in particular, apoptotic process, adaptive immune response and humoral immune response. Mutations and abnormalities in protein PD-1 have been associated with a number of diseases, namely, systemic lupus erythematosus (SLE).
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of PD-1 antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
| AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
| Proteins | HRP, Alkaline Phosphatase, Streptavidin |
| Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
| Small Molecules | Biotin |
| Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
| iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
| mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on August 5, 2024
Certificate of analysis