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Purified Mouse Anti-human/mouse/pig Vimentin Antibody *VI-10, monoclonal*
Vimentin is a 54 kDa protein that can be found in the cytosol, extracellular exosome and cytoskeleton of cells. In Homo sapiens, vimentin binds to double-stranded RNA and identical protein. It is the subject of intensive research in part because it is a member of the cytokine-mediated signaling pathway. Vimentin is thought to be essential to organismal processes, for example, cellular response to interferon-γ, SMAD protein signal transduction and astrocyte development. Sequencing of vimentin has supported it contains a primary structural unit, the IF rod domain. Vimentin is thought to be essential to mRNA stability. It is an inhibitor of neuron projection development but also is a promoter of translation and collagen biosynthetic process. Vimentin is clinically significant because abnormalities in its function have been thought to be involved with diseases like Cataract 30, multiple types (CTRCT30).
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of Vimentin antibody with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
| AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
| Proteins | HRP, Alkaline Phosphatase, Streptavidin |
| Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
| Small Molecules | Biotin |
| Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
| iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
| mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on November 21, 2024
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