Purified Anti-human CD5 Antibody *HISM2*

HISM2 is an anti-human monoclonal antibody that forms an immune complex with the CD5 antigen. CD5 (sometimes referred to as LEU1, Tp67 or Lyt-1) is a 67 kD single-pass type I membrane protein that is located on the surface of cells like B cells and T cells. CD5 is a component of vital cellular pathways, for instance, the apoptotic signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like ZAP-70, TCR and BCR. CD5 is a moderately popular antibody target, with over 11000 publications in the last decade. CD5 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of costimulatory molecules. This antibody was purified through affinity chromatography.

Page updated on November 21, 2024