PE/XFD700 Anti-human CD71 Antibody *HI160, XFD700 Same Structure to Alexa Fluor™ 700*

HI160 is an anti-human monoclonal antibody that is specific for the CD71 antigen. CD71 (also known as Transferrin receptor protein 1) is a 95 kD member of the Transferrin receptor family that is located on the surface of cells such as endothelial cells and stem cells. In certain organisms, CD71 is a positive regulator of isotype switching, is involved in the positive regulation of T cell proliferation and acts to positively regulate B cell proliferation. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as Transferrin. CD71 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD71 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE/XFD700 (ex/em = 566/721 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 561 nm laser and 695/40 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte).