PacBlue Anti-human CD16 Antibody *HI16a*

The HI16a monoclonal antibody recognizes human CD16a, a 50 - 65 kD transmembrane glycoprotein often located on the surface of neutrophils, natural killer cells and macrophages. CD16 is involved with critical cellular pathways, for instance, the Fc-gamma receptor signaling pathway involved in phagocytosis. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like IgG Fc. CD16 is a very popular antibody target, with over 25000 publications in the last decade. CD16a is essential for innate immunity research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PacBlue (ex/em = 404/455 nm). It is compatible with the 405 nm laser and 450/50 nm bandpass filter (for example, as in the BD FACSAria™ II).

Page updated on December 17, 2024