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Nuclear Red™ LCS1 *5 mM DMSO Solution*

Our Nuclear Red™ LCS1 is a fluorogenic, DNA-selective and cell-permeant dye for analyzing DNA content in living cells. The Nuclear Red™ LCS1 has its red fluorescence significantly enhanced upon binding to DNA. It can be used in fluorescence imaging, microplate and flow cytometry applications. This DNA-binding dye might be used for multicolor analysis of live cells with proper filter sets.

Spectrum

Product family

Citations

View all 11 citations: Citation Explorer
Nuclear translocation of Axl contributes to the malignancy of oral cancer cells
Authors: Su, Yu-Fu and Shen, Po-Chien and Huang, Wen-Yen and Hung, Yi-Jen and Huang, Tsai-Wang and Lin, Che-Yi and Shieh, Yi-Shing
Journal: Journal of Dental Sciences (2023)
Bezafibrate Exerts Neuroprotective Effects in a Rat Model of Sporadic Alzheimer’s Disease
Authors: Lin, Li-Fan and Jhao, Yun-Ting and Chiu, Chuang-Hsin and Sun, Lu-Han and Chou, Ta-Kai and Shiue, Chyng-Yann and Cheng, Cheng-Yi and Ma, Kuo-Hsing
Journal: Pharmaceuticals (2022): 109
Supplementary materials: Selective Microfluidic Capture and De-tection of Prostate Cancer Cells from Urine without Digital Rectal Examination
Authors: Chan, Kit Man and Gleadle, Jonathan M and Gregory, Philip A and Phillips, Caroline A and Shirazi, Hanieh Safizadeh and Whiteley, Amelia and Li, Jordan and Vasilev, Krasimir and MacGregor, Melanie
Journal: (2021)
Inclusion of an Optimized Plasmodium falciparum Merozoite Surface Protein 2--Based Antigen in a Trivalent, Multistage Malaria Vaccine
Authors: Eacret, Jacqueline S and Parzych, Elizabeth M and Gonzales, Donna M and Burns, James M
Journal: The Journal of Immunology (2021): 1817--1831
Improving hexaminolevulinate enabled cancer cell detection in liquid biopsy immunosensors
Authors: Chan, Kit Man and Gleadle, Jonathan and Li, Jordan and Michl, Thomas Danny and Vasilev, Krasimir and MacGregor, Melanie
Journal: Scientific Reports (2021): 1--13

References

View all 65 references: Citation Explorer
In vitro activity of pyrvinium pamoate against Entamoeba histolytica and Giardia intestinalis using radiolabelled thymidine incorporation and an SYBR Green I-based fluorescence assay
Authors: Downey AS, Graczyk TK, Sullivan DJ.
Journal: J Antimicrob Chemother (2009): 751
Highly sensitive and selective detection of Hg(2+) in aqueous solution with mercury-specific DNA and Sybr Green I
Authors: Wang J, Liu B.
Journal: Chem Commun (Camb) (2008): 4759
Tetraalkylammonium derivatives as real-time PCR enhancers and stabilizers of the qPCR mixtures containing SYBR Green I
Authors: Shaik GM, Draberova L, Draber P, Boubelik M.
Journal: Nucleic Acids Res (2008): e93
Addition of gold nanoparticles to real-time PCR: effect on PCR profile and SYBR Green I fluorescence
Authors: Haber AL, Griffiths KR, Jamting AK, Emslie KR.
Journal: Anal Bioanal Chem (2008): 887
Interaction of a DNA intercalator DRAQ5, and a minor groove binder SYTO17, with chromatin in live cells--influence on chromatin organization and histone-DNA interactions
Authors: Wojcik K, Dobrucki JW.
Journal: Cytometry A (2008): 555
Page updated on December 17, 2024

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Unit size
Catalog Number17542
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Physical properties

Molecular weight

627.27

Solvent

DMSO

Spectral properties

Excitation (nm)

622

Emission (nm)

645

Storage, safety and handling

Certificate of OriginDownload PDF
H-phraseH303, H313, H340
Hazard symbolT
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R68

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC41116134
Fluorescence images of HeLa cells stained with MitoLite&trade; Green FM using fluorescence microscope with a FITC filter set (Green). Live cells were co-stained with nuclei stain Nuclear Red&trade; LCS1 Cat. 17542 (Red).
Fluorescence images of HeLa cells stained with MitoLite&trade; Green FM using fluorescence microscope with a FITC filter set (Green). Live cells were co-stained with nuclei stain Nuclear Red&trade; LCS1 Cat. 17542 (Red).
Fluorescence images of HeLa cells stained with MitoLite&trade; Green FM using fluorescence microscope with a FITC filter set (Green). Live cells were co-stained with nuclei stain Nuclear Red&trade; LCS1 Cat. 17542 (Red).