mFluor™ UV460 Anti-human CD209 Antibody *UW60.1*

UW60.1 is an anti-human monoclonal antibody that targets the CD209 antigen. CD209 (alternatively called DC-SIGN) is a transmembrane protein that is located on the surface of cells like macrophages, endothelial cells and dendritic cells. CD209 is associated with a variety of biologically interesting macromolecules/ligands, for example, mannose-bearing glycoproteins on several pathogens including HIV gp120. CD209 is a fairly uncommon antibody target, with a little more than 2700 publications in the last decade. Even still, CD209 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of innate immunity and immunology. This antibody was purified through affinity chromatography and conjugated to mFluor™ UV460 (ex/em = 358/456 nm). It is compatible with the 355 nm laser and 450/50 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).

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