Mca-YVADAPK(Dnp)-OH

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Physical properties

Molecular weight	1145.15
Solvent	DMSO

Spectral properties

Correction Factor (280 nm)	0.3
Excitation (nm)	322
Emission (nm)	381

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Overview SDS Protocol

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Mca-YVADAPK(Dnp)-OH to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	87.325 µL	436.624 µL	873.248 µL	4.366 mL	8.732 mL
5 mM	17.465 µL	87.325 µL	174.65 µL	873.248 µL	1.746 mL
10 mM	8.732 µL	43.662 µL	87.325 µL	436.624 µL	873.248 µL

Molarity calculator

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Spectrum

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Spectral properties

Correction Factor (280 nm)	0.3
Excitation (nm)	322
Emission (nm)	381

Images

Figure 1. Chemical structure for Mca-YVADAPK(Dnp)-OH.

References

View all 50 references: Citation Explorer

Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2-Mediated COVID-19.
Authors: Bos, J Martijn and Hebl, Virginia B and Oberg, Ann L and Sun, Zhifu and Herman, Daniel S and Teekakirikul, Polakit and Seidman, Jonathan G and Seidman, Christine E and Dos Remedios, Cristobal G and Maleszewski, Joseph J and Schaff, Hartzell V and Dearani, Joseph A and Noseworthy, Peter A and Friedman, Paul A and Ommen, Steve R and Brozovich, Frank V and Ackerman, Michael J
Journal: Mayo Clinic proceedings (2020): 1354-1368

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression.
Authors: Sinha, Sanju and Cheng, Kuoyuan and Schäffer, Alejandro A and Aldape, Kenneth and Schiff, Eyal and Ruppin, Eytan
Journal: Molecular systems biology (2020): e9628

Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection.
Authors: Kong, Qi and Xiang, Zhiguang and Wu, Yue and Gu, Yu and Guo, Jianguo and Geng, Fei
Journal: Molecular cancer (2020): 80

Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications.
Authors: Sun, Zeyu and Ren, Keyi and Zhang, Xing and Chen, Jinghua and Jiang, Zhengyi and Jiang, Jing and Ji, Feiyang and Ouyang, Xiaoxi and Li, Lanjuan
Journal: Engineering (Beijing, China) (2020)

SARS-CoV-2 Infections and ACE2: Clinical Outcomes Linked With Increased Morbidity and Mortality in Individuals With Diabetes.
Authors: Obukhov, Alexander G and Stevens, Bruce R and Prasad, Ram and Li Calzi, Sergio and Boulton, Michael E and Raizada, Mohan K and Oudit, Gavin Y and Grant, Maria B
Journal: Diabetes (2020): 1875-1886

SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.
Authors: Gupta, Ruchir and Charron, Jacob and Stenger, Cynthia L and Painter, Jared and Steward, Hunter and Cook, Taylor W and Faber, William and Frisch, Austin and Lind, Eric and Bauss, Jacob and Li, Xiaopeng and Sirpilla, Olivia and Soehnlen, Xavier and Underwood, Adam and Hinds, David and Morris, Michele and Lamb, Neil and Carcillo, Joseph A and Bupp, Caleb and Uhal, Bruce D and Rajasekaran, Surender and Prokop, Jeremy W
Journal: The Journal of biological chemistry (2020): 11742-11753

Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology.
Authors: Cleary, Simon J and Pitchford, Simon C and Amison, Richard T and Carrington, Robert and Robaina Cabrera, C Lorena and Magnen, Mélia and Looney, Mark R and Gray, Elaine and Page, Clive P
Journal: British journal of pharmacology (2020)

Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates.
Authors: Damas, Joana and Hughes, Graham M and Keough, Kathleen C and Painter, Corrie A and Persky, Nicole S and Corbo, Marco and Hiller, Michael and Koepfli, Klaus-Peter and Pfenning, Andreas R and Zhao, Huabin and Genereux, Diane P and Swofford, Ross and Pollard, Katherine S and Ryder, Oliver A and Nweeia, Martin T and Lindblad-Toh, Kerstin and Teeling, Emma C and Karlsson, Elinor K and Lewin, Harris A
Journal: bioRxiv : the preprint server for biology (2020)

Putative COVID- 19 Induction of Reward Deficiency Syndrome (RDS) and Associated Behavioral Addictions with Potential Concomitant Dopamine Depletion: Is COVID-19 Social Distancing a Double Edged Sword?
Authors: Blum, Kenneth and Cadet, Jean Lud and Baron, David and Badgaiyan, Rajendra D and Brewer, Raymond and Modestino, Edward J and Gold, Mark S
Journal: Substance use & misuse (2020): 1-5

Hypercytokinemia and Pathogen-Host Interaction in COVID-19.
Authors: Badawi, Alaa
Journal: Journal of inflammation research (2020): 255-261