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Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2-Mediated COVID-19.
Authors: Bos, J Martijn and Hebl, Virginia B and Oberg, Ann L and Sun, Zhifu and Herman, Daniel S and Teekakirikul, Polakit and Seidman, Jonathan G and Seidman, Christine E and Dos Remedios, Cristobal G and Maleszewski, Joseph J and Schaff, Hartzell V and Dearani, Joseph A and Noseworthy, Peter A and Friedman, Paul A and Ommen, Steve R and Brozovich, Frank V and Ackerman, Michael J
Journal: Mayo Clinic proceedings (2020): 1354-1368

ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition.
Authors: El-Sayed Moustafa, Julia Sarah and Jackson, Anne U and Brotman, Sarah M and Guan, Li and Villicaňa, Sergio and Roberts, Amy L and Zito, Antonino and Bonnycastle, Lori and Erdos, Michael R and Narisu, Narisu and Stringham, Heather M and Welch, Ryan and Yan, Tingfen and Lakka, Timo and Parker, Stephen and Tuomilehto, Jaakko and Collins, Francis S and Pajukanta, Päivi and Boehnke, Michael and Koistinen, Heikki A and Laakso, Markku and Falchi, Mario and Bell, Jordana T and Scott, Laura J and Mohlke, Karen L and Small, Kerrin S
Journal: medRxiv : the preprint server for health sciences (2020)

ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome.
Authors: Devaux, Christian A and Rolain, Jean-Marc and Raoult, Didier
Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi (2020): 425-435

The protein expression profile of ACE2 in human tissues.
Authors: Hikmet, Feria and Méar, Loren and Edvinsson, Åsa and Micke, Patrick and Uhlén, Mathias and Lindskog, Cecilia
Journal: Molecular systems biology (2020): e9610

Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD.
Authors: Burgueño, Juan F and Reich, Adrian and Hazime, Hajar and Quintero, Maria A and Fernandez, Irina and Fritsch, Julia and Santander, Ana M and Brito, Nivis and Damas, Oriana M and Deshpande, Amar and Kerman, David H and Zhang, Lanyu and Gao, Zhen and Ban, Yuguang and Wang, Lily and Pignac-Kobinger, Judith and Abreu, Maria T
Journal: Inflammatory bowel diseases (2020): 797-808

Elevated FiO2 increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium.
Authors: Myti, Despoina and Gunjak, Miša and Casado, Francisco and Khaghani Raziabad, Solmaz and Nardiello, Claudio and Vadász, István and Herold, Susanne and Pryhuber, Gloria and Seeger, Werner and Morty, Rory E
Journal: American journal of physiology. Lung cellular and molecular physiology (2020): L670-L674

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates.
Authors: Damas, Joana and Hughes, Graham M and Keough, Kathleen C and Painter, Corrie A and Persky, Nicole S and Corbo, Marco and Hiller, Michael and Koepfli, Klaus-Peter and Pfenning, Andreas R and Zhao, Huabin and Genereux, Diane P and Swofford, Ross and Pollard, Katherine S and Ryder, Oliver A and Nweeia, Martin T and Lindblad-Toh, Kerstin and Teeling, Emma C and Karlsson, Elinor K and Lewin, Harris A
Journal: Proceedings of the National Academy of Sciences of the United States of America (2020): 22311-22322

Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses.
Authors: Qi, Furong and Qian, Shen and Zhang, Shuye and Zhang, Zheng
Journal: Biochemical and biophysical research communications (2020): 135-140

Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine.
Authors: Bonam, Srinivasa Reddy and Muller, Sylviane and Bayry, Jagadeesh and Klionsky, Daniel J
Journal: Autophagy (2020): 1-7

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function.
Authors: Winkler, Emma S and Bailey, Adam L and Kafai, Natasha M and Nair, Sharmila and McCune, Broc T and Yu, Jinsheng and Fox, Julie M and Chen, Rita E and Earnest, James T and Keeler, Shamus P and Ritter, Jon H and Kang, Liang-I and Dort, Sarah and Robichaud, Annette and Head, Richard and Holtzman, Michael J and Diamond, Michael S
Journal: Nature immunology (2020)

Structural basis of a shared antibody response to SARS-CoV-2.
Authors: Yuan, Meng and Liu, Hejun and Wu, Nicholas C and Lee, Chang-Chun D and Zhu, Xueyong and Zhao, Fangzhu and Huang, Deli and Yu, Wenli and Hua, Yuanzi and Tien, Henry and Rogers, Thomas F and Landais, Elise and Sok, Devin and Jardine, Joseph G and Burton, Dennis R and Wilson, Ian A
Journal: Science (New York, N.Y.) (2020): 1119-1123

The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
Authors: Yamamoto, Mizuki and Kiso, Maki and Sakai-Tagawa, Yuko and Iwatsuki-Horimoto, Kiyoko and Imai, Masaki and Takeda, Makoto and Kinoshita, Noriko and Ohmagari, Norio and Gohda, Jin and Semba, Kentaro and Matsuda, Zene and Kawaguchi, Yasushi and Kawaoka, Yoshihiro and Inoue, Jun-Ichiro
Journal: Viruses (2020)

Hypercytokinemia and Pathogen-Host Interaction in COVID-19.
Authors: Badawi, Alaa
Journal: Journal of inflammation research (2020): 255-261

Putative COVID- 19 Induction of Reward Deficiency Syndrome (RDS) and Associated Behavioral Addictions with Potential Concomitant Dopamine Depletion: Is COVID-19 Social Distancing a Double Edged Sword?
Authors: Blum, Kenneth and Cadet, Jean Lud and Baron, David and Badgaiyan, Rajendra D and Brewer, Raymond and Modestino, Edward J and Gold, Mark S
Journal: Substance use & misuse (2020): 1-5

Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates.
Authors: Damas, Joana and Hughes, Graham M and Keough, Kathleen C and Painter, Corrie A and Persky, Nicole S and Corbo, Marco and Hiller, Michael and Koepfli, Klaus-Peter and Pfenning, Andreas R and Zhao, Huabin and Genereux, Diane P and Swofford, Ross and Pollard, Katherine S and Ryder, Oliver A and Nweeia, Martin T and Lindblad-Toh, Kerstin and Teeling, Emma C and Karlsson, Elinor K and Lewin, Harris A
Journal: bioRxiv : the preprint server for biology (2020)

Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology.
Authors: Cleary, Simon J and Pitchford, Simon C and Amison, Richard T and Carrington, Robert and Robaina Cabrera, C Lorena and Magnen, Mélia and Looney, Mark R and Gray, Elaine and Page, Clive P
Journal: British journal of pharmacology (2020)

SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.
Authors: Gupta, Ruchir and Charron, Jacob and Stenger, Cynthia L and Painter, Jared and Steward, Hunter and Cook, Taylor W and Faber, William and Frisch, Austin and Lind, Eric and Bauss, Jacob and Li, Xiaopeng and Sirpilla, Olivia and Soehnlen, Xavier and Underwood, Adam and Hinds, David and Morris, Michele and Lamb, Neil and Carcillo, Joseph A and Bupp, Caleb and Uhal, Bruce D and Rajasekaran, Surender and Prokop, Jeremy W
Journal: The Journal of biological chemistry (2020): 11742-11753

SARS-CoV-2 Infections and ACE2: Clinical Outcomes Linked With Increased Morbidity and Mortality in Individuals With Diabetes.
Authors: Obukhov, Alexander G and Stevens, Bruce R and Prasad, Ram and Li Calzi, Sergio and Boulton, Michael E and Raizada, Mohan K and Oudit, Gavin Y and Grant, Maria B
Journal: Diabetes (2020): 1875-1886

Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications.
Authors: Sun, Zeyu and Ren, Keyi and Zhang, Xing and Chen, Jinghua and Jiang, Zhengyi and Jiang, Jing and Ji, Feiyang and Ouyang, Xiaoxi and Li, Lanjuan
Journal: Engineering (Beijing, China) (2020)

Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection.
Authors: Kong, Qi and Xiang, Zhiguang and Wu, Yue and Gu, Yu and Guo, Jianguo and Geng, Fei
Journal: Molecular cancer (2020): 80

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression.
Authors: Sinha, Sanju and Cheng, Kuoyuan and Schäffer, Alejandro A and Aldape, Kenneth and Schiff, Eyal and Ruppin, Eytan
Journal: Molecular systems biology (2020): e9628

Interactions between local renin angiotensin system and nitric oxide in the brain of Trypanosoma cruzi infected rats.
Authors: Miranda, Aline Silva and Rachid, Milene Alvarenga and Souza, Cássio Ferraz and Oliveira, Bruna da Silva and Ferreira, Rodrigo Novaes and Martinelli, Patrícia Massara and Teixeira, Antônio Lúcio and Camargos, Elizabeth R S and Simões E Silva, Ana Cristina
Journal: Acta tropica (2019): 36-40

Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater.
Authors: Zhou, Xuming and Guang, Xuanmin and Sun, Di and Xu, Shixia and Li, Mingzhou and Seim, Inge and Jie, Wencai and Yang, Linfeng and Zhu, Qianhua and Xu, Jiabao and Gao, Qiang and Kaya, Alaattin and Dou, Qianhui and Chen, Bingyao and Ren, Wenhua and Li, Shuaicheng and Zhou, Kaiya and Gladyshev, Vadim N and Nielsen, Rasmus and Fang, Xiaodong and Yang, Guang
Journal: Nature communications (2018): 1276

Lipoxin A4 attenuates LPS-induced acute lung injury via activation of the ACE2-Ang-(1-7)-Mas axis.
Authors: Chen, Qiong-Feng and Kuang, Xiao-Dong and Yuan, Qi-Feng and Hao, Hua and Zhang, Ting and Huang, Yong-Hong and Zhou, Xiao-Yan
Journal: Innate immunity (2018): 285-296

Evidence of cardiac involvement in the fetal inflammatory response syndrome: disruption of gene networks programming cardiac development in nonhuman primates.
Authors: Mitchell, Timothy and MacDonald, James W and Srinouanpranchanh, Sengkeo and Bammler, Theodor K and Merillat, Sean and Boldenow, Erica and Coleman, Michelle and Agnew, Kathy and Baldessari, Audrey and Stencel-Baerenwald, Jennifer E and Tisoncik-Go, Jennifer and Green, Richard R and Gale, Michael J and Rajagopal, Lakshmi and Adams Waldorf, Kristina M
Journal: American journal of obstetrics and gynecology (2018): 438.e1-438.e16

Differential Gene Expression Profile of Renin-Angiotensin System in the Left Atrium in Mitral Regurgitation Patients.
Authors: Liu, Wen-Hao and Fang, Yen-Nan and Wu, Chia-Chen and Chen, Mien-Cheng and Chang, Jen-Ping and Lin, Yu-Sheng and Pan, Kuo-Li and Ho, Wan-Chun and Chang, Tzu-Hao and Huang, Yao-Kuang and Fang, Chih-Yuan and Chen, Chien-Jen and Lee, Wei-Chieh
Journal: Disease markers (2018): 6924608

Gene expression profiling of the mouse gut: Effect of intestinal flora on intestinal health.
Authors: Zhu, Wenhua and Li, Jun and Wu, Benyan
Journal: Molecular medicine reports (2018): 3667-3673

Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion.
Authors: Lo, Hsiao-Fan and Tsai, Ching-Yen and Chen, Chie-Pein and Wang, Liang-Jie and Lee, Yun-Shien and Chen, Chia-Yu and Liang, Chung-Tiang and Cheong, Mei-Leng and Chen, Hungwen
Journal: The Journal of pathology (2017): 324-336

Preliminary analysis of the association between methylation of the ACE2 promoter and essential hypertension.
Authors: Fan, Rui and Mao, Shu-Qi and Gu, Tian-Lun and Zhong, Fa-De and Gong, Min-Li and Hao, Ling-Mei and Yin, Feng-Ying and Dong, Chang-Zheng and Zhang, Li-Na
Journal: Molecular medicine reports (2017): 3905-3911

Serum protease activity in chronic kidney disease patients: The GANI_MED renal cohort.
Authors: Wolke, Carmen and Teumer, Alexander and Endlich, Karlhans and Endlich, Nicole and Rettig, Rainer and Stracke, Sylvia and Fiene, Beate and Aymanns, Simone and Felix, Stephan B and Hannemann, Anke and Lendeckel, Uwe
Journal: Experimental biology and medicine (Maywood, N.J.) (2017): 554-563

Protein Malnutrition Alters Tryptophan and Angiotensin-Converting Enzyme 2 Homeostasis and Adaptive Immune Responses in Human Rotavirus-Infected Gnotobiotic Pigs with Human Infant Fecal Microbiota Transplant.
Authors: Fischer, David D and Kandasamy, Sukumar and Paim, Francine C and Langel, Stephanie N and Alhamo, Moyasar A and Shao, Lulu and Chepngeno, Juliet and Miyazaki, Ayako and Huang, Huang-Chi and Kumar, Anand and Rajashekara, Gireesh and Saif, Linda J and Vlasova, Anastasia N
Journal: Clinical and vaccine immunology : CVI (2017)

Nodular glomerulosclerosis and renin angiotensin system in Chinese patients with type 2 diabetes.
Authors: Wang, Min and Zhang, Xiaoxi and Song, Xinnan and Zou, Xia and Wu, Weijie and Wang, Yanchao and Lin, Bingjie and Li, Rong and Hu, Fang and Zhao, Hailu
Journal: Molecular and cellular endocrinology (2016): 92-100

Association of polymorphisms of angiotensin I converting enzyme 2 with retinopathy in type 2 diabetes mellitus among Chinese individuals.
Authors: Meng, N and Zhang, Y and Ma, J and Li, H and Zhou, F and Qu, Y
Journal: Eye (London, England) (2015): 266-71

Generation of outbred Ace2 knockout mice by RNA transfection of TALENs displaying colitis reminiscent pathophysiology and inflammation.
Authors: Liu, Chuxin and Xiao, Liping and Li, Feida and Zhang, Huanhuan and Li, Qin and Liu, Huan and Fu, Shujin and Li, Chao and Zhang, Xingju and Wang, Jun and Staunstrup, Nicklas H and Li, Yong and Yang, Huanming
Journal: Transgenic research (2015): 433-46

Inhibition of endoplasmic reticulum-resident glucosidases impairs severe acute respiratory syndrome coronavirus and human coronavirus NL63 spike protein-mediated entry by altering the glycan processing of angiotensin I-converting enzyme 2.
Authors: Zhao, Xuesen and Guo, Fang and Comunale, Mary Ann and Mehta, Anand and Sehgal, Mohit and Jain, Pooja and Cuconati, Andrea and Lin, Hanxin and Block, Timothy M and Chang, Jinhong and Guo, Ju-Tao
Journal: Antimicrobial agents and chemotherapy (2015): 206-16

Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study.
Authors: Smith, Shad B and Mir, Ellen and Bair, Eric and Slade, Gary D and Dubner, Ronald and Fillingim, Roger B and Greenspan, Joel D and Ohrbach, Richard and Knott, Charles and Weir, Bruce and Maixner, William and Diatchenko, Luda
Journal: The journal of pain : official journal of the American Pain Society (2013): T91-101.e1-3

Maternal protein restriction reduces expression of angiotensin I-converting enzyme 2 in rat placental labyrinth zone in late pregnancy.
Authors: Gao, Haijun and Yallampalli, Uma and Yallampalli, Chandra
Journal: Biology of reproduction (2012): 31

Association of angiotensin I converting enzyme, angiotensin II type 1 receptor and angiotensin I converting enzyme 2 gene polymorphisms with the dyslipidemia in type 2 diabetic patients of Chinese Han origin.
Authors: Xu, Y and Bao, Q and He, B and Pan, Y and Zhang, R and Mao, X and Tang, Z and Qu, L and Zhu, C and Tian, F and Wang, S
Journal: Journal of endocrinological investigation (2012): 378-83

Inhibition of angiotensin II-induced contraction of human airway smooth muscle cells by angiotensin-(1-7) via downregulation of the RhoA/ROCK2 signaling pathway.
Authors: Li, Ning and Cai, Ruijun and Niu, Yi and Shen, Bin and Xu, Jian and Cheng, Yuanxiong
Journal: International journal of molecular medicine (2012): 811-8

HNF4alpha dysfunction as a molecular rational for cyclosporine induced hypertension.
Authors: Niehof, Monika and Borlak, Jürgen
Journal: PloS one (2011): e16319

Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent FcγR pathway.
Authors: Jaume, Martial and Yip, Ming S and Cheung, Chung Y and Leung, Hiu L and Li, Ping H and Kien, Francois and Dutry, Isabelle and Callendret, Benoît and Escriou, Nicolas and Altmeyer, Ralf and Nal, Beatrice and Daëron, Marc and Bruzzone, Roberto and Peiris, J S Malik
Journal: Journal of virology (2011): 10582-97

Identification of key amino acid residues required for horseshoe bat angiotensin-I converting enzyme 2 to function as a receptor for severe acute respiratory syndrome coronavirus.
Authors: Yu, Meng and Tachedjian, Mary and Crameri, Gary and Shi, Zhengli and Wang, Lin-Fa
Journal: The Journal of general virology (2010): 1708-12

ACE2-angiotensin-(1-7)-Mas axis in renal ischaemia/reperfusion injury in rats.
Authors: da Silveira, Kátia D and Pompermayer Bosco, Kênia S and Diniz, Lúcio R L and Carmona, Adriana K and Cassali, Giovanni D and Bruna-Romero, Oscar and de Sousa, Lirlândia P and Teixeira, Mauro M and Santos, Robson A S and Simões e Silva, Ana C and Ribeiro Vieira, Maria A
Journal: Clinical science (London, England : 1979) (2010): 385-94

Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium.
Authors: Sheahan, Timothy and Rockx, Barry and Donaldson, Eric and Sims, Amy and Pickles, Raymond and Corti, Davide and Baric, Ralph
Journal: Journal of virology (2008): 2274-85

Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm.
Authors: Mineharu, Youhei and Inoue, Kayoko and Inoue, Sumiko and Yamada, Shigeki and Nozaki, Kazuhiko and Takenaka, Katsunobu and Hashimoto, Nobuo and Koizumi, Akio
Journal: Stroke (2006): 1189-94

Association study of ACE2 (angiotensin I-converting enzyme 2) gene polymorphisms with coronary heart disease and myocardial infarction in a Chinese Han population.
Authors: Yang, Wei and Huang, Wentao and Su, Shaoyong and Li, Biao and Zhao, Weiyan and Chen, Shufeng and Gu, Dongfeng
Journal: Clinical science (London, England : 1979) (2006): 333-40

Polymorphisms in the gene encoding angiotensin I converting enzyme 2 and diabetic nephropathy.
Authors: Fröjdö, S and Sjölind, L and Parkkonen, M and Mäkinen, V-P and Kilpikari, R and Pettersson-Fernholm, K and Forsblom, C and Fagerudd, J and Tikellis, C and Cooper, M E and Wessman, M and Groop, P-H and ,
Journal: Diabetologia (2005): 2278-81

[Association of angiotensin I converting enzyme 2 gene polymorphism with essential hypertension in Chinese].
Authors: Liu, Tong-bao and Shang, Hui-ping and Zhang, Kui-xing and Chen, Liang-hua and Zhu, Xing-lei and Zhang, Yi and Zhu, Ding-liang and Huang, Wei
Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics (2005): 569-71

Genome-wide scan for Japanese familial intracranial aneurysms: linkage to several chromosomal regions.
Authors: Yamada, Shigeki and Utsunomiya, Maki and Inoue, Kayoko and Nozaki, Kazuhiko and Inoue, Sumiko and Takenaka, Katsunobu and Hashimoto, Nobuo and Koizumi, Akio
Journal: Circulation (2004): 3727-33

Three key proteases--angiotensin-I-converting enzyme (ACE), ACE2 and renin--within and beyond the renin-angiotensin system.
Authors: Guang, Cuie and Phillips, Robert D and Jiang, Bo and Milani, Franco
Journal: Archives of cardiovascular diseases : 373-85