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iFluor® 430 Anti-human CD1 Antibody *L161*

L161 is an anti-human monoclonal antibody that is specific for the CD1c antigen. CD1c (also known as M241 or R7) is a 43 kD glycoprotein that is expressed on the surface of cells such as dendritic cells, macrophages, B cells and T cells. In certain organisms, CD1 acts to positively regulate T cell mediated cytotoxicity, and is associated with a variety of biologically interesting macromolecules/ligands, for example, β-2-microglobulin. CD1 is a moderately popular antibody target, with over 15000 publications in the last decade. CD1c is essential for immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 430 (ex/em = 433/498 nm). It is compatible with the 445 nm laser and 510/80 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).

Spectrum

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of cd1c antibody with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on September 24, 2024

Ordering information

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Additional ordering information

Telephone1-800-990-8053
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Antibody properties

Other namesR7; M241
CloneL161
Hostmouse
IsotypeMouse IgG1 kappa
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging

Spectral properties

Correction Factor (260 nm)

0.68

Correction Factor (280 nm)

0.3

Extinction coefficient (cm -1 M -1)

400001

Excitation (nm)

433

Emission (nm)

498

Quantum yield

0.781

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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