iFluor® 430 Anti-human CD1 Antibody *HI149*

HI149 is an anti-human monoclonal antibody that forms an immune complex with the CD1a antigen. CD1a (sometimes called R4 or T6) is a 49 kD member of the Ig superfamily that is found on the surface of cells like macrophages, dendritic cells and T cells. In certain organisms, CD1 is involved in the positive regulation of T cell mediated cytotoxicity, and is associated with a variety of biologically interesting macromolecules/ligands, namely, β-2-Microglobulin. CD1 is a moderately popular antibody target, with over 15000 publications in the last decade. CD1a is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 430 (ex/em = 433/498 nm). It is compatible with the 445 nm laser and 510/80 nm bandpass filter (for example, as in the BD FACSAria™ III).

Page updated on December 3, 2024