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Anti-Neutrophil gelatinase-associated lipocalin (NGAL) antibody *Mouse anti-human, monoclonal IgG2b*
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein expressed mostly in neutrophils. It is also present in lower levels in the kidney, prostate and epithelia of the respiratory and alimentary tracts. NGAL is a vital component in the innate immune response to bacterial infection. It limits bacterial growth by sequestering iron-containing microorganisms. NGAL's small size and protease resistant properties makes it easily excreted and detected in the urine. Under normal conditions, NGAL levels in the urine and plasma are low. However, in response to kidney injury NGAL levels increase sharply reaching diagnostic levels quickly. In clinical biology, NGAL is a novel biomarker of acute kidney injury (AKI) and is used in the early diagnosis of chronic kidney disease. Anti-NGAL monoclonal antibodies are highly sensitive for the detection of human NGAL. They can be used for a broad range of immunoassays such as chemiluminescent immunoassays (CLIA), latex enhanced turbidimetric immunoassays (LETIA), lateral-flow immunoassays (LFIA) and ELISA.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of Anti-Neutrophil gelatinase-associated lipocalin (NGAL) antibody *Mouse anti-human, monoclonal IgG2b* with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
| AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
| Proteins | HRP, Alkaline Phosphatase, Streptavidin |
| Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
| Small Molecules | Biotin |
| Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
| iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
| mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on December 17, 2024
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