Anti-Myeloperoxidase (MPO) antibody *Mouse anti-human, monoclonal IgG2b*
Myeloperoxidase (MPO) is a 150 kDa cationic hemoprotein that consists of two covalently bound subunits each containing a heavy chain (60 kDa) and a light chain (15 kDa). MPO is abundantly expressed in neutrophils and is released during degranulation. It plays a vital role in inflammatory responses by catalyzing chloride ion oxidation to produce hypochlorous acid which is used by neutrophils to kill bacteria and other pathogens. MPO is also known to cause oxidative modification of low density lipoproteins to a high uptake form. This is considered to be a key event in the promotion of atherogenesis and is linked to the progression of cardiovascular diseases. As such, MPO is considered to be a promising cardiovascular biomarker as elevated MPO levels indicates a high risk for atherosclerosis and coronary heart disease (CHD). Anti-MPO monoclonal antibodies are highly sensitive for the detection of human MPO. They can be used for a broad range of immunoassays such as latex enhanced turbidimetric immunoassays (LETIA), chemiluminescent immunoassays (CLIA) and ELISA.
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of Anti-Myeloperoxidase (MPO) antibody *Mouse anti-human, monoclonal IgG2b* with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
Proteins | HRP, Alkaline Phosphatase, Streptavidin |
Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
Small Molecules | Biotin |
Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on October 31, 2024