Anti-Dehydroepiandrosterone antibody *Mouse anti-human, monoclonal IgG1*

Dehydroepiandrosterone (DHEA) is the most abundant hormone in the human body. It is synthesized primarily in the adrenal glands, gonads and brain from cholesterol, and is a metabolic intermediate for all sex hormones. In blood, most of the DHEA present is sulfated as DHEAS with levels approximately 250 to 300-fold higher than free DHEA. The conversion of DHEAS to DHEA, which is catalyzed by sulfotransferase, occurs predominantly in the adrenal, liver and small intestine. In clinical biology, blood measurements of DHEAS and DHEA are a useful in assessing excess adrenal activity in patients with adrenal cancer, hyperplasia and in females with polycystic ovary syndrome. Anti-DHEA monoclonal antibodies are highly sensitive for the detection of DHEA immunogens. They can be used for a broad range immunoassays such as ELISA.