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AAT Bioquest

Anti-Aspartate aminotransferase, cytoplasmic antibody *Mouse anti-human, monoclonal IgG1*

Aspartate aminotransferase (AST) is a pyridoxal phosphate-dependent transaminase enzyme which exists in two isoenzymic forms mitochondrial (m-AST) and cytosolic (c-AST). It is essential for amino acid metabolism because it catalyzes the interconversion of aspartate and α-ketoglutarate to oxaloacetate and glutamate. AST is present in most organs with the highest concentrations found in the liver, heart, skeletal muscles, kidneys, brain and red blood cells. As a biomarker, AST has been used clinically to diagnose hepatitis, myocardial infarction, acute pancreatitis and musculoskeletal diseases. Anti-c-AST monoclonal antibodies are highly sensitive for the detection of human c-AST proteins. They can be used for a broad range of IHC applications and in immunoinhibition assay development.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of Anti-Aspartate aminotransferase, cytoplasmic antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 31, 2024

Ordering information

Price
Unit size
50 ug
1 mg
Catalog Number
Quantity
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Additional ordering information

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Antibody properties

Other names
Hostmouse
Reactivityhuman
ApplicationImmunoinhibition assay

Storage, safety and handling

Intended useResearch Use Only (RUO)
Clinical comparison of anti-c-AST monoclonal antibodies prepared in m-AST reagent and commercial kit.
Clinical comparison of anti-c-AST monoclonal antibodies prepared in m-AST reagent and commercial kit.
Clinical comparison of anti-c-AST monoclonal antibodies prepared in m-AST reagent and commercial kit.
Linear correlation of predicted m-AST activity and measured m-AST activity: different concentrations of m-AST samples were prepared by mixing m-AST protein with c-AST protein in different proportions. The m-AST activities of each sample were tested with AAT Bioquest’s m-AST reagent using a biochemistry platform.
Thermal stability of m-AST reagent: anti-c-AST monoclonal antibodies prepared in m-AST reagent were stored at 4°C and 37°C for 14 days, respectively.
Thermal stability of anti-c-AST monoclonal antibodies: anti-c-AST monoclonal antibodies were stored at 4°C and 37°C for 14 days.