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AAT Bioquest

Anti-Alpha-fetoprotein antibody *Mouse anti-human, monoclonal IgG1*

Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal development. It is widely used as diagnostic marker to screen for various developmental abnormalities and in adults, pancreatic cancer, lung cancer, liver cancer and liver cirrhosis. During pregnancy, high concentrations of AFP in the amniotic fluid may indicate severe congenital defects of a fetus, teratoma and fetal death. Anti-AFP monoclonal antibodies are highly specific for the detection of human AFP immunogens. They can be used for a broad range of immunoassays chemiluminescence immunoassays (CLIA) and rapid sandwich immunoassays.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of Anti-Alpha-fetoprotein antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on October 31, 2024

Ordering information

Price
Unit size
50 ug
1 mg
Catalog Number
Quantity
Add to cart

Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
InternationalSee distributors
Bulk requestInquire
Custom sizeInquire
Technical SupportContact us
Purchase orderSend to sales@aatbio.com
ShippingStandard overnight for United States, inquire for international
Request quotation

Antibody properties

Other names
Hostmouse
Reactivityhuman
ApplicationELISA; CLIA

Storage, safety and handling

Intended useResearch Use Only (RUO)
<p>Graphs showing the determination of clinical&nbsp;samples using two antibody combinations on CLIA platform and compared to a high-quality comparison assay. Results indicate AAT Bioquest&rsquo;s mAb combinations A and B can be applied to double-mAb-sandwich-immunoassays.</p>
<p>mAb combination A: Clone â‘¢ - V100065</p>
<p>mAb combination B: Clone â‘¡ - V100065</p>
<p>Graphs showing the determination of clinical&nbsp;samples using two antibody combinations on CLIA platform and compared to a high-quality comparison assay. Results indicate AAT Bioquest&rsquo;s mAb combinations A and B can be applied to double-mAb-sandwich-immunoassays.</p>
<p>mAb combination A: Clone â‘¢ - V100065</p>
<p>mAb combination B: Clone â‘¡ - V100065</p>
<p>Graphs showing the determination of clinical&nbsp;samples using two antibody combinations on CLIA platform and compared to a high-quality comparison assay. Results indicate AAT Bioquest&rsquo;s mAb combinations A and B can be applied to double-mAb-sandwich-immunoassays.</p>
<p>mAb combination A: Clone â‘¢ - V100065</p>
<p>mAb combination B: Clone â‘¡ - V100065</p>
<p>Calibration curves for AFP in a sandwich chemiluminescence immunoassay (CLIA). Monoclonal antibodies were tested in pairs as capture and detection antibodies to determine the best two-site mAb combinations for the development of a quantitative sandwich immunoassay. The best selected mAb combinations for quantification of human AFP are (capture-detection respectively):</p>
<p>mAb combination A: Clone â‘¢ - V100065</p>
<p>mAb combination B: Clone â‘¡ - V100065</p>