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6-OG488 Azide

6-OG488 azide has the same chemical structure to that of Oregon Green™ 488 azide. It is a convenient tool to introduce the fluorophore of Oregon Green to a biological molecule that contains an alkyne group. It is reactive with terminal alkynes via a copper-catalyzed click reaction. In particular, 6-OG488 azide can be used as a bio-orthogonal or biologically unique hapten for the biological applications requiring signal amplification. Oregon Green is a bright and photostable alternative to fluorescein for use in flow cytometry, fluorescence microscopy and high content analysis of cells. Oregon Green™ is the trademark of ThermoFisher.

Spectrum

Product family

NameExcitation (nm)Emission (nm)Extinction coefficient (cm -1 M -1)Correction Factor (280 nm)
6-FAM Azide493517830000.178
6-HEX azide533559730000.15
6-TET azide521542730000.13
6-JOE azide520545750001-
6-TAMRA azide552578900000.178
6-ROX azide578604820000.168
6-OG488 acid [equivalent to Oregon Green® 488 carboxylic acid, 6-isomer]498526760000.12
6-NED azide545567740001-
6-VIC Azide526543--

References

View all 50 references: Citation Explorer
Photoactivatable Fluorescent Tags for Dual-Modality Positron Emission Tomography Optical Imaging.
Authors: Guillou, Amaury and Nisli, Eda and Klingler, Simon and Linden, Anthony and Holland, Jason P
Journal: Journal of medicinal chemistry (2022): 811-823
Selective Mitochondrial Protein Labeling Enabled by Biocompatible Photocatalytic Reactions inside Live Cells.
Authors: Wang, Haoyan and Zhang, Yixin and Zeng, Kaixing and Qiang, Jiali and Cao, Ye and Li, Yunxia and Fang, Yanshan and Zhang, Yaoyang and Chen, Yiyun
Journal: JACS Au (2021): 1066-1075
Cell-surface Labeling via Bioorthogonal Host-Guest Chemistry.
Authors: Kataki-Anastasakou, Anna and Hernandez, Selena and Sletten, Ellen M
Journal: ACS chemical biology (2021): 2124-2129
Interfacial dilatational and emulsifying properties of ultrasound-treated pea protein.
Authors: Sha, Lei and Koosis, Aeneas O and Wang, Qingling and True, Alma D and Xiong, Youling L
Journal: Food chemistry (2021): 129271
Design and Synthesis of Fluorophore-Tagged Disparlure Enantiomers to Study Pheromone Enantiomer Discrimination in the Pheromone-Binding Proteins from the Gypsy Moth, Lymantria dispar.
Authors: Pinnelli, Govardhana R and Plettner, Erika
Journal: Journal of chemical ecology (2021)
Page updated on November 21, 2024

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Catalog Number236
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Physical properties

Molecular weight

637.68

Solvent

DMSO

Spectral properties

Correction Factor (260 nm)

0.31

Correction Factor (280 nm)

0.12

Extinction coefficient (cm -1 M -1)

76000

Excitation (nm)

498

Emission (nm)

526

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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