Apoptosis and Necrosis

Apoptosis, or programmed cell death, is a key part of embryonic development and tissue homeostasis in multicellular organisms. Cells undergoing apoptosis are characterized by distinct morphological changes and energy-dependent biochemical mechanisms. These characteristics include membrane blebbing, cell shrinkage, activation of caspase cascade, chromatin condensation and DNA fragmentation, as well as the production of membrane-bound apoptotic bodies. Since no single parameter entirely defines apoptosis, many different approaches are used in the study of cell death.

We offer a wide range of apoptosis reagents and assays for measuring multiple markers of apoptosis including:

• Annexin V Assays
• Caspase Activity Assays
• TUNEL Assays
• Mitochondrial Membrane Potential (ΔΨm) Indicators
• Glutathione monitoring assay

AssayWise Letter Articles:	Catalogs:
Apoptosis Assays and probes A Superior Direct Method for the Quantitative Analysis of DNA Fragments in Late-Stage Apoptosis Multiplexing Caspase Activity	Cell Apoptosis & Proliferation